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183 Racemic Hemiacetals as Oxygen-Centered Pronucleophiles Triggering Cascade 1,4-Addition/Michael Reaction through Dynamic Kinetic Resolution under Iminium catalysis. Reaction Development and Mechanistic Insights
Chem. Sci.
2017. DOI: 10.1039/C7SC00009J
182 Regioselectivity Change in the Organocatalytic Enantioselective (3+2) Cycloaddition with Nitrones Through Cooperative H-Bonding Catalysis/Iminium Activation
Chem. Eur. J.
2017, 23, 2764-2768. DOI: 10.1002@chem.201605350

181 A Molecular Electron Density Theory Study of the [3+2] Cycloaddition Reaction of Nitrones with Ketenes
Org. Biol. Chem.
2017, 15, 1525-1534. DOI: 10.1039/C6OB02768G
180 Pivotal Neighbouring Group Participation in Substitution vs Elimination Reactions: Computational Evidence for Ion Pairs in the Thionation of Alcohols with Lawesson's Reagent
Eur. J. Org. Chem. 2016. DOI: 10.1002/ejoc.201700127

179

Synthesis of Amino Acid-Nucleoside Conjugates, Ghirardello, M.; Delso, I.; Tejero, T.; Merino, P.
Asian
J. Org. Chem.. 2016, 1525-1534. DOI: 10.1002/ajoc.201600497

178

Computational Mechanistic Study of Thionation of Carbonyl Compounds with Lawesson's Reagent, Juste-Navarro, V.; Delso, I.; Tejero, T.; Merino, P.
J. Org. Chem.. 2016, 81, 7733-7740. DOI: 10.1021/acs.joc.6b01420

177

Azomethine Ylides from Nitrones: Using Catalytic n-BuLi for the Totally Stereoselective Synthesis of trans-2-Alkyl-3-Oxazolines, Juste-Navarro, V.; Delso, I.; Tejero, T.; Merino, P.
Chem. Eur. J.
2016, 22, 11527-11532. DOI: 10.1002/chem.201602159. Cover: DOI: 10.1002/chem.201602827.
Cover Profile: DOI: 10.1002/chem.201602894

176

Glycomimetics Targeting Glycosyltransferases: Synthetic, Computational and Structural Studies of Less-Polar Conjugates, Ghirardello, M.; de las Rivas, M.; Lacetera, A.; Delso, I.; Lira-Navarrete, E.; Tejero, T.; Martin-Santamaria, S.; Hurtado-Guerrero, R.; Merino, P.
Chem. Eur. J.
2016, 22, 7215-7224. DOI: 10.1002/chem.201600467

175

Mechanistic Insights in the Mode of Action of Bifunctional Pyrrolidine-Squaramide-derived Organocatalysts, Roca-López, D.; Uria, U.; Reyes, E.; Carrillo, L.; Jørgensen, K. A.; Vicario, J. L.; Merino, P.
Chem. Eur. J. 2016, 22, 884-889. DOI: 10.1002/chem.201504705

174

Revisiting Oxime-Nitrone Tautomerism. Evidences of Nitrone Tautomer Participation in Oxime Nucleophilic Addition Reactions, Roca-López, D.; Darù, A.; Tejero, T.; Merino, P.
RSC Adv.
2016, 6, 22161-22173. DOI: 10.1039/C6RA02638A

173

Rapid, Efficient and Solvent Free MW Mediated Synthesis of Aldo- and Ketonitrones, Maiuolo, L.; Nino, A. D.; Merino, P.; Russo, B.; Stabile, G.; Nardi, M.; D’Agostino, N.; Bernardi, T. Arabian J. Chem. 2016, 9, 25-31. DOI: 10.1016/j.arabjc.2015.01.015

172

Stereoselective Ethynylation and Propargylation of Chiral Cyclic Nitrones. Application to the Synthesis of Glycomimetics, García-Viñuales, S.; Delso, I.; Merino, P.; Tejero, T. Synthesis 2016, DOI: 10.1055/s-0035-1562500

171

Rational design of glycomimetic compounds targeting the Saccharomyces cerevisae transglycosylase Gas2, Delso, I.; Valero-González, J.; Marca, E.; Tejero, T.; Hurtado-Guerrero, R.; Merino, P. Chem. Biol. Drug Design 2016, 87, 163-170. DOI: 10.1111/cbdd.12650

170

Revealing Stepwise Mechanisms in Dipolar Cycloaddition Reactions: Computational Study of the Reaction between Nitrones and Isocyanates, Daru, A.; Roca-López, D.; Tejero, T.; Merino, P. J. Org. Chem. 2016, 81, 673-680. DOI: 10.1021/acs.joc.5b02645

169

Mechanism Switch in Mannich-type Reactions. ELF and NCI Topological Analyses of the Reaction between Nitrones and Lithium Enolates, Roca-López, D.; Polo, V.; Tejero, T.; Merino, P. Eur. J. Org. Chem. 2015, 4143-4152.

168

Understanding Bond Formation in Polar One-Step Reactions. Topological analyses of the Reaction between Nitrones and Lithium Ynolates, Roca-López, D.; Polo, V.; Tejero, T.; Merino, P. J. Org. Chem. 2015, 80, 4076-4083.

167

New Efficient Organocatalyst Supported on Simple Ionic Liquid as Recoverable System for Asymmetric Diels-Alder Reaction in Presence of Water, Nino, A. D.; Maiuolo, L.; Merino, P.; Nardia, M.; Procopio, A.; Roca-López, D.; Russo, B. ChemCatChem 2015, 7, 830-835.

166

A Natural Ternary Complex Trapped in Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase, Albesa-Jové, D.; Mendoza, M. F.; Rodrigo-Unzueta, A.; Gomollón-Bel, F.; Cifuente, J.; Urresti, S.; Comino, N.; Gómez, H.; Romero-García, J.; Lluch, J. M.; Sancho-Vaello, E.; Biarnés, X.; Planas, A.; Merino, P.; Masgrau, L.; Guerin, M. E. Angew. Chem. Int. Ed. 2015, 54, 9898-9902.

165

DFT Investigation of the Mechanism of E/Z Isomerization of Nitrones, Roca-Lopez, D.; Tejero, T.; Merino, P. J. Org. Chem. 2014, 79, 8358-8365.

164

[2n2π + 2n2π] Cycloadditions: An alternative to forbidden [4π + 4π] processes. The Case of Nitrones Dimerizations, Roca-López, D.; Tejero, T.; Caramella, P.; Merino, P. Org. Biomol. Chem. 2014, 12, 517-525.

163

Friedel-Crafts alkylation mechanism using aminoindanol derived thiourea catalyst, Roca-López, D.; Marqués-López, E.; Alcaine, A.; Merino, P.; Herrera, R. P. Org. Biomol. Chem. 2014, 12, 4503-4510.

162

Theoretical Elucidation of the Mechanism of the Cycloaddition between Nitrone Ylides and Electron-deficient Alkenes, Merino, P.; Tejero, T.; Diez Martinez, A. J. Org. Chem. 2014, 79, 2189-2202.

161

Highly Diastereoselective 1,3-Dipolar Cycloadditions of Chiral Non-Racemic Nitrones to 1,2-Diaza-1,3-dienes: An Experimental and Computational Investigation, Majer, R.; Konechnaya, O.; Delso, I.; Tejero, T.; Attanasi, O. A.; Santeusanio, S.; Merino, P. Org. Biomol. Chem. 2014, 12, 8888-8901.

160

Stereoselective 1,3-dipolar cycloadditions of nitrones derived from amino acids. Asymmetric synthesis of N-(alkoxycarbonylmethyl)-3-hydroxypyrrolidin-2-ones, Merino, P.; Greco, G.; Tejero, T.; Hurtado-Guerrero, R.; Matute, R.; Chiacchio, U.; Corsaro, A.; Pistara, V.; Romeo, R. Tetrahedron 2013, 69, 9381-9390.

159

Synthesis of O- and C-glycosides derived from β-(1,3)-D-glucans Marca, E.; Valero-Gonzalez, J.; Delso, I.; Tejero, T.; Hurtado-Guerrero, R.; Merino, P. Carbohydr. Res. 2013, 382, 9-18.

158

The High Selectivity of the Cp2ZrHCl Reducing Agent for Imides: A Combined Experimental and Theoretical Study on γ-Lactam and Isoxazolidinone Derivatives, Lanza, G.; Chiacchio, M. A.; Giofre, S. V.; Romeo, R.; Merino, P. Eur. J. Org. Chem. 2013, 2013, 95-104.

157

Evasive Neutral 2-Aza-Cope Rearrangements. Kinetic and Computational Studies with Cyclic Nitrones, Delso, I.; Melicchio, A.; Isasi, A.; Tejero, T.; Merino, P. Eur. J. Org. Chem. 2013, 2013, 5721-5730.

156

Truncated Reverse Isoxazolidinyl Nucleosides: A New Class of Allosteric HIV-1 Reverse Transcriptase Inhibitors, Romeo, R.; Giofrè, S. V.; Macchi, B.; Balestrieri, E.; Mastino, A.; Merino, P.; Carnovale, C.; Romeo, G.; Chiacchio, U. ChemMedChem 2012, 7, 565-569.

155

Highly stereoselective synthesis of imino-C-di- and trisaccharides as hydrolytically stable glycomimetics, Marca, E.; Delso, I.; Tejero, T.; Merino, P. Tetrahedron 2012, 68, 6674-6687.

154

Dual reactivity of O-α-allenyl esters under palladium(0) catalysis: From carbopalladation/allylic alkylation domino sequence to decarboxylative allenylation, Kammerer-Pentier, C.; Diez Martinez, A.; Oble, J.; Prestat, G.; Merino, P.; Poli, G. J. Organomet. Chem. 2012, 714, 53-59.

153

Stereoselective Hydride Transfer by Aryl-Alcohol Oxidase, a Member of the GMC Superfamily, Hernandez-Ortega, A.; Ferreira, P.; Merino, P.; Medina, M.; Guallar, V.; Martinez, A. T. ChemBioChem 2012, 13, 427-435.

152

Water-compatible one-pot organocatalytic asymmetric synthesis of cyclic nitrones. Application in intramolecular 1,3-dipolar cycloadditions, Sadaba, D.; Delso, I.; Tejero, T.; Merino, P. Tetrahedron Lett. 2011, 52, 5976-5979.

151

Organocatalyzed Michael addition reaction by novel (2R,3aS,7aS)-octahydroindole-2-carboxylic acid, a new fused proline, Roca-Lopez, D.; Merino, P.; Sayago, F. J.; Cativiela, C.; Herrera, R. P. Synlett 2011, 249-253.

150

Nitrone ylides: Two possible 1,3-dipolar cycloadditions but only one stepwise formation of all-cis 2,4,5-trisubstituted N-hydroxypyrrolidines, Merino, P.; Tejero, T.; Diez-Martinez, A.; Gultekin, Z. Eur. J. Org. Chem. 2011, 6567-6573.

149

High-yield synthesis of pyrrolidinyl PNA monomers, Merino, P.; Greco, G.; Tejero, T.; Corsaro, A.; Chiacchio, U.; Pistara, V.; Romeo, G. Tetrahedron Lett. 2011, 52, 6003-6006.

148

Structural insights into the mechanism of Protein O-fucosylation, Lira-Navarrete, E.; Valero-Gonzalez, J.; Villanueva, R.; Martinez-Julvez, M.; Tejero, T.; Merino, P.; Panjikar, S.; Hurtado-Guerrero, R. PLoS One 2011, 9, e25365 (14 pages).

147

Sequential nucleophilic addition/intramolecular cycloaddition to chiral nonracemic cyclic nitrones: A highly stereoselective approach to polyhydroxynortropane alkaloids, Delso, I.; Tejero, T.; Goti, A.; Merino, P. J. Org. Chem. 2011, 76, 4139-4143.

146

Thiourea catalyzed organocatalytic enantioselective Michael addition of diphenyl phosphite to nitroalkenes, Alcaine, A.; Marques-Lopez, E.; Merino, P.; Tejero, T.; Herrera, R. P. Org. Biomol. Chem. 2011, 9, 2777-2783.

145

Asymmetric organocatalytic synthesis of γ-nitrocarbonyl compounds through Michael and Domino reactions, Roca-Lopez, D.; Sadaba, D.; Delso, I.; Herrera, R. P.; Tejero, T.; Merino, P. Tetrahedron Asymmetry 2010, 21, 2561-2601.

144

Expanding the limits of organoboron chemistry: Synthesis of functionalized arylboronates, Merino, P.; Tejero, T. Angew. Chem. Int. Ed. 2010, 49, 7164-7165.

143

Enantioselective organocatalytic Diels-Alder reactions, Merino, P.; Marques-Lopez, E.; Tejero, T.; Herrera, R. P. Synthesis 2010, 1-26.

142

Experimental and theoretical studies on Mannich-type reactions of chiral non-racemic N-(benzyloxyethyl) nitrones, Diez-Martinez, A.; Tejero, T.; Merino, P. Tetrahedron Asymmetry 2010, 21, 2934-2943.

141

Synthesis of N-(benzyloxyethyl)- and N-(alkoxycarbonylmethyl)nitrones, Diez-Martinez, A.; Gultekin, Z.; Delso, I.; Tejero, T.; Merino, P. Synthesis 2010, 678-688.

140

Synthesis of D-arabinose-derived polyhydroxylated pyrrolidine, indolizidine and pyrrolizidine alkaloids. Total synthesis of hyacinthacine A2, Delso, I.; Tejero, T.; Goti, A.; Merino, P. Tetrahedron 2010, 66, 1220-1227.

139

Tunable Diastereoselection of Biased Rigid Systems by Lewis Acid Induced Conformational Effects: A Rationalization of the Vinylation of Cyclic Nitrones En Route to Polyhydroxylated Pyrrolidines, Delso, I.; Marca, E.; Mannucci, V.; Tejero, T.; Goti, A.; Merino, P. Chem. Eur. J. 2010, 16, 9910-9919.

138

Organocatalyzed Strecker reactions, Merino, P.; Marques-Lopez, E.; Tejero, T.; Herrera, R. P. Tetrahedron 2009, 65, 1219-1234.

137

Intramolecular 1,3-dipolar cycloaddition of N-alkenyl nitrones en route to glycosyl piperidines, Marca, E.; Delso, I.; Tejero, T.; Vazquez, J. T.; Dorta, R. L.; Merino, P. Tetrahedron Lett. 2009, 50, 7152-7155.

136

Stereoselective Synthesis and Biological Evaluations of Novel 3'-Deoxy-4'-azaribonucleosides as Inhibitors of Hepatitis C Virus RNA Replication, Chiacchio, U.; Borrello, L.; Crispino, L.; Rescifina, A.; Merino, P.; Macchi, B.; Balestrieri, E.; Mastino, A.; Piperno, A.; Romeo, G. Journal of Medicinal Chemistry 2009, 52, 4054-4057.

135

Catalytic enantioselective hydrophosphonylation of aldehydes and imines, Merino, P.; Marques-Lopez, E.; Herrera, R. P. Advanced Synthesis & Catalysis 2008, 350, 1195-1208.

134

Exploring nitrone chemistry: towards the enantiodivergent synthesis of 6-substituted 4-hydroxypipecolic acid derivatives, Merino, P.; Mannucci, V.; Tejero, T. Eur. J. Org. Chem. 2008, 3943-3959.

133

Nucleophilic additions to cyclic nitrones en route to iminocyclitols - total syntheses of DMDP, 6-deoxy-DMDP, DAB-1, CYB-3, nectrisine, and radicamine B, Merino, P.; Delso, I.; Tejero, T.; Cardona, F.; Marradi, M.; Faggi, E.; Parmeggiani, C.; Goti, A. Eur. J. Org. Chem. 2008, 2929-2947.

132

3-(Aminomethyl)-2-(carboxymethyl)isoxazolidinyl nucleosides: building blocks for peptide nucleic acid analogues, Merino, P.; Tejero, T.; Mates, J.; Chiacchio, U.; Corsaro, A.; Romeo, G. Tetrahedron Asymmetry 2007, 18, 1517-1520.

131

Hydroxylamine oxygen as nucleophile in palladium(0)- and palladium(II)-catalyzed allylic alkylation: a novel access to isoxazolidines, Merino, P.; Tejero, T.; Mannucci, V.; Prestat, G.; Madec, D.; Poli, G. Synlett 2007, 944-948.

130

Experimental and theoretical evidences of 2-aza-Cope rearrangement of nitrones, Merino, P.; Tejero, T.; Mannucci, V. Tetrahedron Lett. 2007, 48, 3385-3388.

129

A DFT study on the 1,3-dipolar cycloaddition reactions of C-(hetaryl) nitrones with methyl acrylate and vinyl acetate, Merino, P.; Tejero, T.; Chiacchio, U.; Romeo, G.; Rescifina, A. Tetrahedron 2007, 63, 1448-1458.

128

Nucleophilic additions and redox reactions of polyhydroxypyrroline N-oxides on the way to pyrrolidine alkaloids: total synthesis of radicamine B, Merino, P.; Delso, I.; Tejero, T.; Cardona, F.; Goti, A. Synlett 2007, 2651-2654.

127

Stereoselective synthesis of pyrrolidinyl glycines from nitrones: complementarity of nucleophilic addition and 1,3-dipolar cycloaddition, Merino, P.; Padar, P.; Delso, I.; Thirumalaikumar, M.; Tejero, T.; Kovacs, L. Tetrahedron Lett. 2006, 47, 5013-5016.

126

Enantiodivergent synthesis of D- and L-erythro-sphingosines through Mannich-type reactions of N-benzyl-2,3-O-isopropylidene-D-glyceraldehyde nitrone, Merino, P.; Jimenez, P.; Tejero, T. J. Org. Chem. 2006, 71, 4685-4688.

125

High stereocontrol in the allylation of chiral non-racemic a-alkoxy and a-amino nitrones, Merino, P.; Delso, I.; Mannucci, V.; Tejero, T. Tetrahedron Lett. 2006, 47, 3311-3314.

124

A DFT study of the molecular mechanisms of the nucleophilic addition of ester-derived lithium enolates and silyl ketene acetals to nitrones: effects of the Lewis acid catalyst, Domingo, L. R.; Arno, M.; Merino, P.; Tejero, T. Eur. J. Org. Chem. 2006, 3464-3472.

123

An efficient approach to enantiomeric isoxazolidinyl analogs of tiazofurin based on nitrone cycloadditions, Merino, P.; Tejero, T.; Unzurrunzaga, F. J.; Franco, S.; Chiacchio, U.; Saita, M. G.; Iannazzo, D.; Piperno, A.; Romeo, G. Tetrahedron: Asymmetry 2005, 16, 3865-3876.

122

Nucleophilic additions of lithiated allylphenylsulfone to nitrones: experimental and theoretical investigations, Merino, P.; Mannucci, V.; Tejero, T. Tetrahedron 2005, 61, 3335-3347.

121

Effect of additional chiral ligands in catalytic enantioselective Mannich-type reactions with nitrones, Merino, P.; Franco, S.; Jimenez, P.; Tejero, T.; Chiacchio, M. A. Lett. Org. Chem. 2005, 2, 302-305.

120

Straightforward synthesis of enantiopure 2-aminomethyl and 2-hydroxymethyl pyrrolidines with complete stereocontrol, Marradi, M.; Cicchi, S.; Ignacio Delso, J.; Rosi, L.; Tejero, T.; Merino, P.; Goti, A. Tetrahedron Lett. 2005, 46, 1287-1290.

119

Zinc(II) Triflate-Controlled 1,3-Dipolar Cycloadditions of C-(2-Thiazolyl)nitrones: Application to the Synthesis of a Novel Isoxazolidinyl Analog of Tiazofurin, Chiacchio, U.; Rescifina, A.; Saita, M. G.; Iannazzo, D.; Romeo, G.; Mates, J. A.; Tejero, T.; Merino, P. J. Org. Chem. 2005, 70, 8991-9001.

118

Enantioselective 1,3-Dipolar Cycloaddition of Nitrones to Methacrolein Catalyzed by (h5-C5Me5)M{(R)-Prophos} Containing Complexes (M = Rh, Ir; (R)-Prophos = 1,2-bis(Diphenylphosphino)propane): On the Origin of the Enantioselectivity, Carmona, D.; Lamata, M. P.; Viguri, F.; Rodriguez, R.; Oro, L. A.; Lahoz, F. J.; Balana, A. I.; Tejero, T.; Merino, P. J. Am. Chem. Soc. 2005, 127, 13386-13398.

117

New Concise Total Synthesis of (+)-Lentiginosine and Some Structural Analogues, Cardona, F.; Moreno, G.; Guarna, F.; Vogel, P.; Schuetz, C.; Merino, P.; Goti, A. J. Org. Chem. 2005, 70, 6552-6555.

116

Diastereo- and enantioselective synthesis of 1’-C-branched N,O-nucleosides, Saita, M. G.; Chiacchio, U.; Iannazzo, D.; Corsaro, A.; Merino, P.; Piperno, A.; Previtera, T.; Rescifina, A.; Romeo, G.; Romeo, R. Nucleosides, Nucleotides & Nucleic Acids 2004, 23, 739-742.

115

Organocatalyzed asymmetric alpha-aminoxylation of aldehydes and ketones--an efficient access to enantiomerically pure alpha-hydroxycarbonyl compounds, diols, and even amino alcohols, Merino, P.; Tejero, T. Angew. Chem. Int. Ed. 2004, 43, 2995-2997.

114

Fully stereoselective nucleophilic addition to a novel chiral pyrroline N-oxide: total syntheses of (2S,3R)-3-hydroxy-3-methylproline and its (2R)-epimer, Merino, P.; Revuelta, J.; Tejero, T.; Cicchi, S.; Goti, A. Eur. J. Org. Chem. 2004, 776-782.

113

Nucleophilic additions of chiral non-racemic enolates to N-benzyl-C-(alkoxymethyl) nitrones, Merino, P.; Franco, S.; Mates, J. A.; Merchan, F. L.; Romero, P.; Tejero, T.; Uriel, S.; Matute, R. Arkivoc 2004, 48-58.

112

Diastereoselective synthesis of homo-N,O-nucleosides, Chiacchio, U.; Genovese, F.; Iannazzo, D.; Librando, V.; Merino, P.; Rescifina, A.; Romeo, R.; Procopio, A.; Romeo, G. Tetrahedron 2004, 60, 441-448.

111

The Complete Characterization of a Rhodium Lewis Acid-Dipolarophile Complex as an Intermediate for the Enantioselective Catalytic 1,3-Dipolar Cycloaddition of C,N-Diphenylnitrone to Methacrolein, Carmona, D.; Lamata, M. P.; Viguri, F.; Rodriguez, R.; Oro, L. A.; Balana, A. I.; Lahoz, F. J.; Tejero, T.; Merino, P.; Franco, S.; Montesa, I. J. Am. Chem. Soc. 2004, 126, 2716-2717.

110

Organometallic gold(III) and gold(I) complexes as catalysts for the 1,3-dipolar cycloaddition to nitrones: synthesis of novel gold-nitrone derivatives, Ade, A.; Cerrada, E.; Contel, M.; Laguna, M.; Merino, P.; Tejero, T. J. Organomet. Chem. 2004, 689, 1788-1795.

109

A comparative study of the stereoselective addition of trimethylsilyl cyanide and diethylaluminum cyanide to chiral cyclic nitrones, Merino, P.; Tejero, T.; Revuelta, J.; Romero, P.; Cicchi, S.; Mannucci, V.; Brandi, A.; Goti, A. Tetrahedron: Asymmetry 2003, 14, 367-379.

108

An investigation of the Lewis acid mediated 1,3-dipolar cycloaddition between N-benzyl-C-(2-pyridyl)nitrone and allylic alcohol. Direct entry to isoxazolidinyl C-nucleosides, Merino, P.; Tejero, T.; Laguna, M.; Cerrada, E.; Moreno, A.; Lopez, J. A. Org. Biomol. Chem. 2003, 1, 2336-2342.

107

A DFT study on the 1,3-dipolar cycloaddition reactions of C-(methoxycarbonyl)-N-methyl nitrone with methyl acrylate and vinyl acetate, Merino, P.; Revuelta, J.; Tejero, T.; Chiacchio, U.; Rescifina, A.; Romeo, G. Tetrahedron 2003, 59, 3581-3592.

106

1,3-Dipolar cycloaddition between N-benzyl-C-glycosyl nitrones and methyl acrylate en route to glycosyl pyrrolidines, Merino, P.; Franco, S.; Merchan, F. L.; Romero, P.; Tejero, T.; Uriel, S. Tetrahedron: Asymmetry 2003, 14, 3731-3743.

105

Stereoselective synthesis of (-)-deacetylanisomycin, Merino, P.; Franco, S.; Lafuente, D.; Merchan, F.; Revuelta, J.; Tejero, T. Eur. J. Org. Chem. 2003, 2877-2881.

104

Nucleophilic additions to nitrones: An alternative gateway to isoxazolidines, pyrrolidines and related compounds. In Targets in Heterocyclic Systems, Merino, P., Attanasi, O.; Spinelli, D., Eds. RSC Publishing: London, 2003; Vol. 7, pp 140-156.

103

Iterative organometallic addition to chiral hydroxylated cyclic nitrones: highly stereoselective syntheses of alpha,alpha'- and alpha,alpha-substituted hydroxypyrrolidines, Goti, A.; Cicchi, S.; Mannucci, V.; Cardona, F.; Guarna, F.; Merino, P.; Tejero, T. Org. Lett. 2003, 5, 4235-4238.

102

Isoxazolidine analogs of pseudouridine: a new class of modified nucleosides, Chiacchio, U.; Corsaro, A.; Mates, J.; Merino, P.; Piperno, A.; Rescifina, A.; Romeo, G.; Romeo, R.; Tejero, T. Tetrahedron 2003, 59, 4733-4738.

101

Enantioselective synthesis of N,O-psiconucleosides, Chiacchio, U.; Borrello, L.; Iannazzo, D.; Merino, P.; Piperno, A.; Rescifina, A.; Richichi, B.; Romeo, G. Tetrahedron: Asymmetry 2003, 14, 2419-2425.

100

Enantioselective synthesis of 4-hydroxy-D-pyroglutamic acid derivatives by an asymmetric 1,3-dipolar cycloaddition, Merino, P.; Revuelta, J.; Tejero, T.; Chiacchio, U.; Rescifina, A.; Piperno, A.; Romeo, G. Tetrahedron: Asymmetry 2002, 13, 167-172.

99

Experimental and theoretical study of the 1,3-dipolar cycloaddition between D-glyceraldehyde nitrones and acrylates. diastereoselective approach to 4-hydroxy pyroglutamic acid derivatives, Merino, P.; Mates, J. A.; Revuelta, J.; Tejero, T.; Chiacchio, U.; Romeo, G.; Iannazzo, D.; Romeo, R. Tetrahedron: Asymmetry 2002, 13, 173-190.

98

Efficient synthesis of (2R,3S)- and (2S,3S)-2-amino-1,3,4-butanetriols through stereodivergent hydroxymethylation of D-glyceraldehyde nitrones, Merino, P.; Franco, S.; Merchan, F. L.; Revuelta, J.; Tejero, T. Tetrahedron Lett. 2002, 43, 459-462.

97

Understanding the High Diastereofacial Discrimination in Nucleophilic Additions to Nitrones. The First Ab Initio Study on the Nucleophilic Addition Reactions of Chiral Nitrones with Grignard Reagents, Merino, P.; Tejero, T. Tetrahedron 2001, 57, 8125-8128.

96

Facial selectivity in the addition of ketene acetals to nitrones towards chiral non-racemic isoxazolidin-5-ones. A semiempirical study, Merino, P.; Mates, J. A. Arkivoc 2001, 12-30.

95

Crystal and molecular structures of N-benzyl-C-(2-pyridyl)nitrone and its ZnBr2 complex. A study of their reactivity, Merino, P.; Anoro, S.; Cerrada, E.; Laguna, M.; Moreno, A.; Tejero, T. Molecules 2001, 6, 208-220.

94

Nucleophilic additions to chiral nitrones: new approaches to nitrogenated compounds, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Synlett 2000, 442-454.

93

Stereodivergent Approaches to the Synthesis of Isoxazolidine Analogues of a-Amino Acid Nucleosides. Total Synthesis of Isoxazolidinyl Deoxypolyoxin C and Uracil Polyoxin C, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. J. Org. Chem. 2000, 65, 5575-5589.

92

Stereoselective synthesis of L-isoxazolidinyl thymidine from N-benzyl-1,2-di-O-isopropylidene-D-glyceraldehyde nitrone (BIGN), Merino, P.; Del Alamo, E. M.; Franco, S.; Merchan, F. L.; Simon, A.; Tejero, T. Tetrahedron: Asymmetry 2000, 11, 1543-1554.

91

1,3-Dipolar cycloadditions of N-benzyl furfuryl nitrones with electron-rich alkenes, Merino, P.; Anoro, S.; Merchan, F. L.; Tejero, T. Molecules 2000, 5, 132-152.

90

1,3-Dipolar cycloaddition between hetaryl nitrones and methyl acrylate: Theoretical study and application to the synthesis of functionalized pyrrolidines, Merino, P.; Anoro, S.; Merchan, F.; Tejero, T. Heterocycles 2000, 53, 861-876.

89

1,3-Dipolar Cycloaddition of Furfuryl Nitrones with Acrylates. A Convenient Approach to Protected 4-Hydroxypyroglutamic Acids, Merino, P.; Anoro, S.; Franco, S.; Merchan, F. L.; Tejero, T.; Tunon, V. J. Org. Chem. 2000, 65, 1590-1596.

88

A general method for the vinylation of nitrones. Synthesis of allylhydroxylamines and allylamines, Merino, P.; Anoro, S.; Franco, S.; Gascon, J. M.; Martin, V.; Merchan, F. L.; Revuelta, J.; Tejero, T.; Tunon, V. Synth. Comm. 2000, 30, 2989-3021.

87

Lewis acid stereocontrolled additions of a silyl ketene acetal to 2,3-di-O-isopropylidene-D-glyceraldehyde nitrones. Synthesis of L-isoxazolidinyl nucleosides, Merino, P.; Alamo, E. M. d.; Bona, M.; Franco, S.; Merchan, F. L.; Tejero, T.; Vieceli, O. Tetrahedron Lett. 2000, 41, 9239-9243.

86

Stereochemistry of a-(tert-butoxycarbonylamino) hydroxylamines: 1H NMR analysis of hydroxylamines derived from 2-pyrrolidinyl nitrones, Merino, P.; Franco, S.; Gascon, J. M.; Merchan, F. L.; Tejero, T. Tetrahedron: Asymmetry 1999, 10, 1861-1865.

85

Highly diastereoselective nucleophilic addition of organometallic reagents to 2-pyrrolidinyl nitrones: a semiempirical approach, Merino, P.; Franco, S.; Gascon, J. M.; Merchan, F. L.; Tejero, T. Tetrahedron: Asymmetry 1999, 10, 1867-1871.

84

Chiral hydroxylamines. V. (2S,3S)-N-benzyl-N-[3-(tert-butoxycarbonylamino)-2-butyl]hydroxylamine, Merino, P.; Merchan, F. L.; Tejero, T.; Lanaspa, A. Acta Crystallographica, Section C: Crystal Structure Communications 1998, C54, 85-86.

83

Crystal Structure of methyl (2R,3S,4R)-N-Acetyl-2-amino-5-O-tertbutyldimethylsilyl-3,4-O-isopropylidene-3,4,5-trihydroxypentanoate, Merino, P.; Merchan, F. L.; Tejero, T.; Franco, S. Zeits. Krist. 1998, 213, 135-136.

82

Structures of chiral hydroxylamines. VI. (3R,4S)-N-benzyl-4,5-dihydroxy-3-(hydroxyamino)-4,5-O-isopropylidene-1-pentyne, Merino, P.; Merchan, F. L.; Tejero, T.; Franco, S. Acta Crystallographica, Section C: Crystal Structure Communications 1998, C54, 1003-1004.

81

Totally stereocontrolled synthesis of a,b-diamino acids by addition of Grignard reagents to nitrones derived from L-serine, Merino, P.; Lanaspa, A.; Merchan, F. L.; Tejero, T. Tetrahedron: Asymmetry 1998, 9, 629-646.

80

Nucleophilic Additions of 2-Furyllithium to Carbonyl Derivatives of L-Serine. Formal Synthesis of (2R,3R)-α-Hydroxy Aspartic Acid, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Molecules 1998, 3, 26-30.

79

Crystal Structure of 1-(tert-Butoxycarbonylamino)-1-deoxy-2,3-O-isoprop-ylidene-1-(2-thiazolyl)-D-threo-triitol, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Zeits. Krist. 1998, 213, 133-134.

78

Asymmetric Addition Reactions of Lithium (Trimethylsilyl)acetylide with Chiral a-Amino Nitrones. Synthesis of Diastereomerically Pure N-Hydroxy-a-amino Acids, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. J. Org. Chem. 1998, 63, 5627-5630.

77

Asymmetric synthesis of an isoxazolidine nucleoside analog of thymine polyoxin C, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Tetrahedron Lett. 1998, 39, 6411-6414.

76

Synthesis of isoxazolidin-5-ones via stereocontrolled Michael additions of benzylhydroxylamine to L-serine derived a,b-unsaturated esters, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Tetrahedron: Asymmetry 1998, 9, 3945-3949.

75

Modified nucleosides from nitrones: a new and efficient stereoselective approach to isoxazolidinyl thymidine derivatives, Merino, P.; Franco, S.; Garces, N.; Merchan, F. L.; Tejero, T. Chem. Commun. 1998, 493-494.

74

Enantiodivergent Approach to D- and L-Secondary N-Hydroxy-a-amino Acids by Using N-Benzyl-2,3-O-isopropylidene-D-glyceraldehyde Nitrone as an Effective N-Hydroxyglycine Cation Equivalent, Merino, P.; Castillo, E.; Franco, S.; Merchan, F. L.; Tejero, T. J. Org. Chem. 1998, 63, 2371-2374.

73

Ready access to enantiopure 5-substituted-3-pyrrolin-2-ones from N-benzyl-2,3-O-isopropylidene-D-glyceraldehyde nitrone (BIGN), Merino, P.; Castillo, E.; Franco, S.; Merchan, F. L.; Tejero, T. Tetrahedron: Asymmetry 1998, 9, 1759-1769.

72

Nucleophilic additions of Grignard reagents to N-benzyl-2,3-O-isopropylidene-D-glyceraldehyde nitrone (BIGN). Synthesis of (2S,3R) and (2S,3S)-3-phenylisoserine, Merino, P.; Castillo, E.; Franco, S.; Merchan, F. L.; Tejero, T. Tetrahedron 1998, 54, 12301-12322.

71

1,3-Dipolar cycloaddition of C-(2-thiazolyl)nitrones to chiral acrylates. Synthesis of enantiopure a-amino-2-alkylthiazoles and 5-formylpyrrolidin-2-ones, Tejero, T.; Dondoni, A.; Rojo, I.; Merchan, F. L.; Merino, P. Tetrahedron 1997, 53, 3301-3318.

70

Chiral hydroxylamines. IV. 1-(N-benzyl-N-hydroxyamino)-2:3;4:5-di-O-isopropylidene-a-D-mannofuranose, Merino, P.; Merchan, F. L.; Tejero, T.; Franco, S. Acta Crystallographica, Section C: Crystal Structure Communications 1997, C53, 1703-1705.

69

Crystal Structure of (1R,2S)-N-Benzyl-N-[2-(tert-butoxycarbonylamino)-1-(furan-2-yl)-1-propyl]hydroxylamine, Merino, P.; Lanaspa, A.; Merchan, F. L.; Tejero, T. Zeits. Krist. 1997, 212, 323-324.

68

Stereocontrolled synthesis of 2,3-diaminobutanoic acids, Merino, P.; Lanaspa, A.; Merchan, F. L.; Tejero, T. Tetrahedron Lett. 1997, 38, 1813-1816.

67

Stereoselective Grignard reactions to a-amino nitrones. Synthesis of optically active a-aminohydroxylamines and 1,2-diamines, Merino, P.; Lanaspa, A.; Merchan, F. L.; Tejero, T. Tetrahedron: Asymmetry 1997, 8, 2381-2401.

66

A Facile Synthesis of Glycosyl Hydroxylamines, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Synth. Commun. 1997, 27, 3529-3537.

65

Diastereoselective nucleophilic addition of acetylide to N-benzyl-2, 3-O-isopropylidene-D-glyceraldehyde nitrone (BIGN). Stereodivergent synthesis of b-hydroxy-a-(hydroxyamino)- and b-hydroxy-a-amino acids, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Tetrahedron: Asymmetry 1997, 8, 3489-3496.

64

Crystal Structure of 2-Acetamido-1-O-acetyl-2-deoxy-3,4:5,6-di-O-isopropylidene-D-mannitol, Merino, P.; Franco, S.; Junquera, F.; Merchan, F. L.; Tejero, T. Zeits. Krist. 1997, 212, 321-322.

63

Crystal Structure of (2S*,3R*)-N-Benzyl-2-(benzyloxy)-3-(hydroxylamino) butane, Merino, P.; Castillo, E.; Merchan, F. L.; Tejero, T. Zeits. Krist. 1997, 212, 443-444.

62

Crystal Structure of (2S*,3R*)-N-Benzyl-2-(benzyloxy)-3-(hydroxylamino) propane, Merino, P.; Castillo, E.; Merchan, F. L.; Tejero, T. Zeits. Krist. 1997, 212, 441-442.

61

Stereocontrolled addition of Grignard reagents to a-alkoxy nitrones. Synthesis of syn- and anti-3-amino-1,2-diols, Merino, P.; Castillo, E.; Merchan, F. L.; Tejero, T. Tetrahedron: Asymmetry 1997, 8, 1725-1729.

60

A new entry to glycosylamines, Merchan, F. L.; Merino, P.; Tejero, T. Glycoconjugate J. 1997, 14, 497-499.

59

Novel five- and six- membered bisheterocyclic systems from dithiocarbamates and related compounds, Franco, S.; Merchan, F. L.; Merino, P.; Tejero, T. Trends in Heterocyclic Chemistry 1997, 5, 57-74.

58

Stereoselective Addition of 2-Furyllithium and 2-Thiazolyllithium to Sugar Nitrones. Synthesis of Carbon-Linked Glycoglycines, Dondoni, A.; Junquera, F.; Merchan, F. L.; Merino, P.; Scherrmann, M.-C.; Tejero, T. J. Org. Chem. 1997, 62, 5484-5496.

57

Applications of Sugar Nitrones in Synthesis: The Total Synthesis of (+)-Polyoxin J, Dondoni, A.; Franco, S.; Junquera, F.; Merchan, F. L.; Merino, P.; Tejero, T. J. Org. Chem. 1997, 62, 5497-5507.

56

Absolute configuration determination in furfuryl amines and hydroxylamines by circular dichroism, Tejero, T.; Franco, S.; Junquera, F.; Lanaspa, A.; Merchan, F. L.; Merino, P.; Rojo, I. Tetrahedron: Asymmetry 1996, 7, 1529-1534.

55

Structures of chiral nitrones. II. (Z)-N-[(2S)-2-(tert-butoxycarbonylamino)propylidene]benzylamine N-oxide, Merino, P.; Merchan, F. L.; Tejero, T.; Lanaspa, A. Acta Crystallographica, Section C: Crystal Structure Communications 1996, C52, 218-219.

54

Chiral hydroxylamines. II. (1R,2R)-N-benzyl-N-[(3-tert-butoxycarbonyl-2,2-dimethyloxazol-4-yl)(furan-2-yl)methyl]hydroxylamine, Merino, P.; Merchan, F. L.; Tejero, T.; Lanaspa, A. Acta Crystallographica, Section C: Crystal Structure Communications 1996, C52, 2536-2538.

53

Diastereoselective Hydrocyanation of Chiral Nitrones. Synthesis of novel α-(hydroxyamino) nitriles, Merino, P.; LAnaspa, A.; Merchan, F. L.; Tejero, T. J. Org. Chem. 1996, 61, 9028-9032.

52

Chiral hydroxylamines. III. 1-(N-Benzyl-N-hydroxyamino)-1-deoxy-1-(2-furyl)-2,3:4,5-di-O-isopropylidene-L-manno-pentitol, Merino, P.; Junquera, F.; Merchan, F. L.; Tejero, T. Acta Crystallographica, Section C: Crystal Structure Communications 1996, C52, 3197-3198.

51

Direct vinylation and ethynylation of nitrones. Stereodivergent synthesis of allyl and propargyl amines, Merino, P.; Anoro, S.; Castillo, E.; Merchan, F.; Jejero, T. Tetrahedron: Asymmetry 1996, 7, 1887-1890.

50

Enantioselective addition of Grignard reagents to a 2-thiazolyl nitrone, Merchan, F. L.; Merino, P.; Rojo, I.; Tejero, T.; Dondoni, A. Tetrahedron: Asymmetry 1996, 7, 667-670.

49

A straightforward synthesis of L-isoserinal, Junquera, F.; Merchan, F. L.; Merino, P.; Tejero, T. Tetrahedron 1996, 52, 7045-7052.

48

Alkylation of camphor and pinanone imines of 2-(aminomethyl)thiazole. Enantioselective synthesis of 2-(1-aminoalkyl)thiazoles, Dondoni, A.; Merchan, F. L.; Merino, P.; Rojo, I.; Tejero, T. Synthesis 1996, 641-646.

47

(Z)-N-[(2R,3R)-2-(tert-Butoxycarbonylamino)-3-(tert-butyldiphenylsiloxy)butylidene]benzylamine N-oxide, Merino, P.; Merchan, F. L.; Tejero, T.; Lanaspa, A. Acta Crystallographica, Section C: Crystal Structure Communications 1995, C51, 1949-1950.

46

Chiral hydroxylamines. I. 1-(N-benzyl-N-hdyroxyamino)-1-deoxy-2,3-O-isopropylidene-1-(1-methylimidazol-2-yl)-D-threo-triitol, Merino, P.; Merchan, F. L.; Tejero, T. Acta Crystallographica, Section C: Crystal Structure Communications 1995, C51, 2400-2401.

45

Stereoselective addition of cyanide reagents to nitrones, Merchan, F. L.; Merino, P.; Tejero, T. Tetrahedron Lett. 1995, 36, 6949-6952.

44

Determination of the absolute configuration of a-amino-2-alkylthiazoles by circular dichroism, Merchan, F. L.; Merino, P.; Rojo, I.; Tejero, T.; Dondoni, A. Tetrahedron: Asymmetry 1995, 6, 2145-2148.

43

Synthesis of 2,2'-(alkylenediamino)dibenzazoles: New heterocyclic tetradentate ligands, Melendez, E.; Merchan, F. L.; Tejero, T.; Merino, P.; Garcia, M. An. Quim. 1995, 90, 487-490.

42

An improved synthesis of ketonitrones, Franco, S.; Merchan, F. L.; Merino, P.; Tejero, T. Synth. Commun. 1995, 25, 2275-2284.

41

Chelation- and Non-chelation-Controlled Addition of 2-(Trimethylsilyl)thiazole to a-Amino Aldehydes: Stereoselective Synthesis of the b-Amino-a-hydroxy Aldehyde Intermediate for the Preparation of the Human Immunodeficiency Virus Proteinase Inhibitor Ro 31-8959, Dondoni, A.; Perrone, D.; Merino, P. J. Org. Chem. 1995, 60, 8074-8080.

40

Total synthesis of (+)-polyoxin J, Dondoni, A.; Junquera, F.; Merchan, F. L.; Merino, P.; Tejero, T. Chem. Commun. 1995, 2127-2128.

39

Stereoselective homologation-amination of aldehydes by addition of their nitrones to C-2 metalated thiazoles - a general entry to a-amino aldehydes and amino sugars, Dondoni, A.; Franco, S.; Junquera, F.; Merchan, F. L.; Merino, P.; Tejero, T.; Bertolasi, V. Chem. Eur. J. 1995, 1, 505-520.

38

Tunable stereoselectivity in the addition of 2-lithiothiazole to L-serinal derived N-benzyl nitrone. Synthesis of C-2 epimer 2,3-diamino-4-hydroxybutanals, Dondoni, A.; Merchan, F. L.; Merino, P.; Tejero, T.; Bertolasi, V. Chem. Commun. 1994, 1731-1733.

37

Nitrones in Organic Synthesis. Synthesis of Secondary Allyl Amines, Dondoni, A.; Merchan, F.; Merino, P.; Tejero, T. Synth. Commun. 1994, 24, 2551-2555.

36

Installation of the Pyruvate Unit in Glycidic Aldehydes via a Wittig Olefination-Michael Addition Sequence Utilizing a Thiazole-Armed Carbonyl Ylide. A New Stereoselective Route to 3-Deoxy-2-Ulosonic Acids and the Total Synthesis of DAH, KDN, and 4-epi-KDN, Dondoni, A.; Marra, A.; Merino, P. J. Am. Chem. Soc. 1994, 116, 3324-3336.

35

Addition of 2-Lithiofuran to Chiral alpha-Alkoxy Nitrones. A Stereoselective Approach to alpha-epimer-beta-alokoxy-alfa aminoacids, Dondoni, A.; Junquera, F.; Merchan, F. L.; Merino, P.; Tejero, T. Synthesis 1994, 1450-1455.

34

Total synthesis of thymine polyoxin C, Dondoni, A.; Junquera, F.; Merchan, F. L.; Merino, P.; Tejero, T. Tetrahedron Lett. 1994, 35, 9439-9442.

33

Stereo-controlled homologation of 1,2:3,4-di-O-isopropylidene-a-D-galacto-hexodialdo-1,5-pyranose to 7-deoxynonodialdose epimers via thiazole-aldehyde synthesis, Dondoni, A.; Ianelli, S.; Kniezo, L.; Merino, P.; Nardelli, M. J. Chem. Soc., Perkin Trans. 1 1994, 1231-1239.

32

Synthesis of N-Benzyl Nitrones, Dondoni, A.; Franco, S.; Junquera, F.; Merchan, F. L.; Merino, P.; Tejero, T. Synth. Commun. 1994, 24, 2537-2550.

31

Total chemical synthesis of aza sugars via thiazole intermediates. Stereodivergent routes to (-)-nojirimycin, (-)-mannojirimycin and their 3-deoxy derivatives from serine, Dondoni, A.; Merino, P.; Perrone, D. Tetrahedron 1993, 49, 2939-2956.

30

Two-carbon chain extension of chiral aldehydes via 2-alkenylthiazoles: synthesis of g-functionalized alkanals, Dondoni, A.; Merino, P.; Orduna, J.; Perrone, D. Synthesis 1993, 277-279.

29

Iterative methodology for the stereocontrolled synthesis of polyol chains employing 2-acetylthiazole as lactaldehyde equivalent, Dondoni, A.; Merino, P. Synthesis 1993, 903-908.

28

Diastereoselective homologation of D-(R)-glyceraldehyde acetonide using 2-(trimethylsilyl)thiazole: 2-O-benzyl-3,4-isopropylidene-D-erythrose (1,3-dioxolane-4-acetaldehyde, 2,2-dimethyl-a-(phenylmethoxy)-, [R-(R*,R*)]-), Dondoni, A.; Merino, P. Org. Synth. 1993, 72, 21-31.

27

Stereocontrol by diethylaluminum chloride in the addition of 2-lithiofuran and N-methyl-2-lithioimidazole to a-alkoxy nitrones. Total synthesis of 5-O-carbamoylpolyoxamic acid, Dondoni, A.; Franco, S.; Merchan, F. L.; Merino, P.; Tejero, T. Tetrahedron Lett. 1993, 34, 5479-5482.

26

Stereocontrolled addition of 2-lithiothiazole to the nitrone derived from D-glyceraldehyde acetonide. A revision and extension, Dondoni, A.; Franco, S.; Merchan, F. L.; Merino, P.; Tejero, T. Tetrahedron Lett. 1993, 34, 5475-5478.

25

Stereocontrolled addition of 2-thiazolyl organometallic reagents to C-galactopyranosylnitrone. A formal synthesis of destomic acid and lincosamine, Dondoni, A.; Franco, S.; Merchan, F.; Merino, P.; Tejero, T. Synlett 1993, 78-80.

24

Construction of all O-alkoxy D-tetrose and D-pentose stereoisomers from 2,3-O-isopropylidene-D-glyceraldehyde using 2-(trimethylsilyl)thiazole as a formyl anion equivalent, Dondoni, A.; Orduna, J.; Merino, P. Synthesis 1992, 201-210.

23

4-O-Benzyl-2,3-O-isopropylidene-D-erythrose and -D-threose from 2,3-O-isopropylidene-D-glyceraldehyde via thiazole intermediates. Synthesis of 2-deoxykanosamine, Dondoni, A.; Merino, P. Synthesis 1992, 196-200.

22

Stereoselective aminohomologation of chiral a-alkoxy aldehydes via thiazole addition to nitrones. Application to the synthesis of N-acetyl-D-mannosamine, Dondoni, A.; Junquera, F.; Merchan, F. L.; Merino, P.; Tejero, T. Tetrahedron Lett. 1992, 33, 4221-4224.

21

Diheterocyclic compounds from dithiocarbamates and derivatives thereof. VI. Unsymmetrical N1,N4-bis(2-benzazolyl)sulfanilamides, Melendez, E.; Merchan, F. L.; Merino, P.; Orduna, J.; Urchegui, R. J. Het. Chem. 1991, 28, 653-656.

20

The reaction of anthranilic acid with thionyl chloride: the actual structure of Kametani's sulfinamide anhydride, Garin, J.; Merino, P.; Orduna, J.; Tejero, T.; Uriel, S. Tetrahedron Lett. 1991, 32, 3263-3264.

19

Synthesis of unsymmetrical diheteroarylbenzenes: benzazole and quinazoline derivatives, Garin, J.; Melendez, E.; Merchan, F. L.; Merino, P.; Orduna, J.; Tejero, T. J. Het. Chem. 1991, 28, 359-363.

18

Homologation of L-threonine to a-epimer b-amino-a,g-dihydroxy aldehydes and acids via stereoselective reduction of 2-thiazolyl amino ketones, Dondoni, A.; Perrone, D.; Merino, P. Chem. Commun. 1991, 1313-1314.

17

Stereocontrolled total synthesis of galactostatin from serine, Dondoni, A.; Merino, P.; Perrone, D. Chem. Commun. 1991, 1576-1578.

16

Stereoselective construction of polyhydroxyalkyl 2-triazolyl ketones (thiazole ketoses) from D-glyceraldehyde and D-arabinose acetonides by Wittig-Michael sequence. A route to D-gluco-KDO, Dondoni, A.; Merino, P.; Orduna, J. Tetrahedron Lett. 1991, 32, 3247-3250.

15

Chemistry of the enolates of 2-acetylthiazole: aldol reactions with chiral aldehydes to give 3-deoxy aldos-2-uloses and 3-deoxy 2-ulosonic acids. A short total synthesis of 3-deoxy-D-manno-2-octulosonic acid (KDO), Dondoni, A.; Merino, P. J. Org. Chem. 1991, 56, 5294-5301.

14

Diheterocyclic compounds from dithiocarbamates and derivatives thereof. V. 4,4'-Dioxo-2,2'-dithioxo(dioxo)-6,6'-biquinazolines, Garin, J.; Melendez, E.; Merchan, F. L.; Merino, P.; Orduna, J.; Tejero, T.; Vinegra, M. J. Het. Chem. 1990, 27, 1351-1354.

13

Chemoselectivity in The Oxidation of Unsymmetrical Thioureas with NBS/Sulfuric Acid: Benzothiazoles vs. 1,2,4-Thiadiazoles, Garin, J.; Melendez, E.; Merchan, F. L.; Merino, P.; Orduna, J.; Tejero, T. Synth. Commun. 1990, 20, 2324-2327.

12

Diheterocyclic compounds from dithiocarbamates and derivatives thereof. II. 2,2'-Diamino-6,6'-bibenzoazoles, Garin, J.; Melendez, E.; Merchan, F. L.; Merino, P.; Orduna, J.; Tejero, T. J. Het. Chem. 1990, 27, 321-326.

11

Diheterocyclic compounds from dithiocarbamates and derivatives thereof. III. 3,3'-Arylenebis(2,4-dioxo-1,2,3,4-tetrahydroquinazolines), Garin, J.; Melendez, E.; Merchan, F. L.; Merino, P.; Orduna, J.; Tejero, T. J. Het. Chem. 1990, 27, 1341-1344.

10

Diheterocyclic compounds from dithiocarbamates and derivatives thereof. IV. 3,3'-Arylenebis(4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazolines), Garin, J.; Melendez, E.; Merchan, F. L.; Merino, P.; Orduna, J.; Tejero, T. J. Het. Chem. 1990, 27, 1345-1349.

9

Diheterocyclic compounds from dithiocarbamates and derivatives thereof. I. 2,2'-(Arylenediamino)bisbenzoazoles, 2,2'-(arylenediamino)bis(imidazopyridines) and 8,8'-(arylenediamino)bispurines, Garin, J.; Melendez, E.; Merchan, F. L.; Merino, P.; Orduna, J.; Tejedor, R.; Tejero, T. J. Het. Chem. 1990, 27, 221-226.

8

A divergent route to nojirimycin analogs from L-serinal and 2-acetylthiazole, Dondoni, A.; Fantin, G.; Fogagnolo, M.; Merino, P. Chem. Commun. 1990, 854-856.

7

A concise new route to 3-deoxy-D-manno-2-octulosonic acid (KDO) from D-arabinose and 2-acetylthiazole, Dondoni, A.; Fantin, G.; Fogagnolo, M.; Merino, P. Tetrahedron Lett. 1990, 31, 4513-4516.

6

Chain-elongation of dialdoses containing the a-galactopyranosyl group by a Wittig reaction with 2-thiazolylmethylenetriphenylphosphorane. The thiazole route to long-chain alkene sugars, Dondoni, A.; Fantin, G.; Fogagnolo, M.; Merino, P. J. Carbohydr. Chem. 1990, 9, 735-744.

5

Regio- and stereoselective conjugate addition of nitrogen nucleophiles to 2-alkenyl-N-methylthiazolium iodides. Synthesis of D-3-epi-daunosamine and some lincosamine analogs, Dondoni, A.; Fantin, G.; Fogagnolo, M.; Merino, P. Tetrahedron 1990, 46, 6167-6184.

4

A Facile New Method For The Preparation of Aromatic Diisothiocyanates, Garin, J.; Melendez, E.; Merchan, F. L.; Merino, P.; Tejero, T. Bull. Soc. Chim. Belg. 1989, 98, 289-290.

3

Tetramethyl Bis[N-(2-Benzothiazolyl) Dithiocarbon-Imidates]: Novel Reagents For Heterocyclic Polymer Synthesis, Garin, J.; Melendez, E.; Merchan, F. L.; Merino, P.; Orduna, J.; Tejero, T. Synth. Commun. 1989, 19, 2389-2399.

2

On The Reaction of Aromatic Amines with Carbon Disulfide: A Facile Modified Preparation of Bis(Dithiocarbamic) Acid Derivatives, Garin, J.; Melendez, E.; Merchan, F. L.; Merino, P.; Tejero, T. Bull. Soc. Chim. Belg. 1988, 97, 791-792.

1

Dithiocarbamoyl Derivatives: Useful Reagents In Heterocyclic Synthesis, Garin, J.; Melendez, E.; Merchan, F.; Merino, P.; Orduna, J.; Tejero, T. Il Farmaco 1988, 437, 1183-1194.

 

Reviews

31 New Mechanistic Interpretation for Nitrone Reactivity, Org. Biomol. Chem.. 2017. DOI: 10.1039/c7ob00429u
30

Chemical Approaches to Inhibitors of Isoprenoid Biosynthesis: Targeting Farnesyl and Geranylgeranyl Pyrophosphate Synthases, RSC. Adv. 2017. DOI: 10.1039/c6ra28316k

29

Nucleoside Diphosphate Sugar Analogues that Target Glycosyltransferases,
Asian
J. Org. Chem.. 2016, 1413-1427. DOI: 10.1002/ajoc.201600396

28

Design and Synthesis of Dopaminergic Agonists, Matute, M. S.; Matute, R.; Merino, P. Curr. Med. Chem. 2016, 23.
DOI: 10.2174/0929867323666160504103621 

27

Recent Advances on Asymmetric Nitroso Aldol Reaction, Merino, P.; Tejero, T.; Delso, I.; Matute, R. Synthesis 2016, 48, 653-676.

26

Recent advances in the preparation of enantiomerically pure hydroxylamines from nitrones, Matute, R.; Garcia-Viñuales, S.; Hayes, H.; Ghirardello, M.; Daru, A.; Tejero, T.; Delso, I.; Merino, P. Curr. Org. Synth. 2016, 13, 669-686

25

Oxidation reactions of Furan, Merino, P. Org. React. 2015, 87, 1-256.

24

Recent   Advances   on   the   Enantioselective   Synthesis   of   C-Nucleosides Inhibitors of Inosine Monophosphate Dehydrogenase (IMPDH), Merino, P.; Ghirardello, M.; Tejero, T.; Delso, I.; Matute, R. Curr. Top. Med. Chem. 2014, 14, 1212-1224.

23

Biosynthetic Pathways to Glycosidase Inhibitors, Gomollón-Bel, F.; Delso, I.; Tejero, T.; Merino, P. Curr. Chem. Biol. 2014, 8, 10-16.

22

Cross-coupling reactions for the synthesis of C-glycosides and related compounds, Merino, P.; Tejero, T.; Marca, E.; Gomollon-Bel, F.; Delso, I.; Matute, R. Heterocycles 2012, 86, 791-820.

21

Recent advances on the synthesis of piperidines through ruthenium-catalyzed ring-closing metathesis (RCM) reactions, Merino, P.; Tejero, T.; Greco, G.; Marca, E.; Delso, I.; Gómez-SanJuan, A.; Matute, R. Heterocycles 2012, 84, 75-100.

20

Recent progress on fucosyltransferase inhibitors, Merino, P.; Tejero, T.; Delso, I.; Hurtado-Guerrero, R.; Gomez-SanJuan, A.; Sadaba, D. Mini-Rev. Med. Chem. 2012, 12, 1455-1464.

19

Chemical synthesis of five-membered nitrogen heterocycles by reductive cyclization methods, Tejero, T.; Merino, P.; Delso, I.; Sadaba, D. Targets Heterocycl. Syst. 2011, 15, 164-192.

18

Mannich-type reactions with Nitrones, Oximes and Hydrazones, Merino, P.; Tejero, T. Synlett 2011, 1965-1977.

17

Organocatalytic activation of imines and related compounds through hydrogen-bond interactions, Merino, P.; Delso, I.; Tejero, T.; Roca-Lopez, D.; Isas, A.; Matute, R. Curr. Org. Chem.2011, 15, 2184-2209.

16

Chemical Synthesis of Heterocyclic-Sugar Nucleoside Analogues, Romeo, G.; Chiacchio, U.; Corsaro, A.; Merino, P. Chem. Rev. 2010, 110, 3337-3370.

15

Recent developments on rotaxane-based shuttles, Rescifina, A.; Zagni, C.; Iannazzo, D.; Merino, P. Curr. Org. Chem. 2009, 13, 448-481.

14

Chemistry and biology of imino-sugar di- and oligosaccharides, Merino, P.; Delso, I.; Marca, E.; Tejero, T.; Matute, R. Curr. Chem. Biol. 2009, 3, 253-271.

13

Concerted molecular rearrangements. In Seminars in Organic Synthesis, "A. Corbella" Summer School, 34th, Garnano, Italy, June 22-26, 2009, Merino, P., 2009; pp 73-96.

12

Catalytic Enantioselective Aza-Henry Reactions, Marques-Lopez, E.; Merino, P.; Tejero, T.; Herrera, R. P. Eur. J. Org. Chem. 2009, 2401-2420.

11

The role of the indole in important organocatalytic enantioselective Friedel-Crafts alkylation reactions, Marques-Lopez, E.; Diez-Martinez, A.; Merino, P.; Herrera, R. P. Current Organic Chemistry 2009, 13, 1585-1609.

10

Current developments in the synthesis and biological activity of aza-C-nucleosides: immucillins and related compounds, Merino, P.; Tejero, T.; Delso, I. Curr. Med. Chem. 2008, 15, 954-967.

9

Furan oxidations in organic synthesis. Recent advances and applications, Merino, P.; Tejero, T.; Delso, J. I.; Matute, R. Curr.Org. Chemistr. 2007, 11, 1076-1091.

8

Heterocyclic nucleosides: chemical synthesis and biological properties, Merino, P. Curr. Med. Chem. 2006, 13, 539-545.

7

Stereoselective allylation and vinylation reactions of imines and related compounds, Merino, P.; Tejero, T.; Delso, J. I.; Mannucci, V. Curr. Org. Synth. 2005, 2, 479-498.

6

New developments in nucleophilic additions to nitrones, Merino, P. Compt. Rend. Chim. 2005, 8, 775-788.

5

Heterocyclic nucleosides. Chemical synthesis and biological properties, Merino, P. Cur. Med. Chem. 2002, 1, 389-411.

4

Oxidations of furan rings in organic synthesis: Expanding synthetic utility of aromatic heterocycles. In Rec. Res. Dev. Synth. Org. Chem., Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T., Pandalai, S., Ed. 2000; Vol. 3, pp 65-74.

3

Recent developments on chemistry and biological activity of nucleoside analogues with an extra heteroatom in the sugar ring. In Rec. Res. Dev. Org. Chemistry, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T., Pandalai, S., Ed. 2000; Vol. 4, pp 227-237.

2

Recent advances in the reaction of metalated aromatic heterocycles with carbonyl compounds and their imino derivatives, Merino, P. Progr. Het. Chem. 1999, 11, 21-44.

1

Asymmetric nucleophilic additions to chiral nitrones: Scope and applications. In Rec. Res. Dev Synth Org Chem, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T., Pandalai, S., Ed. 1998; Vol. 1, pp 109-121.

Book chapters

20 Oxidation reactions of Furan, Merino, P. Org. React. 2015, 87, 1-256.

19

Mannich-type reactions. Merino, P., In Science of Synthesis. C-1 Building Blocks in Organic Synthesis,  Leeuwen, P. W. N. M. v., Ed. Georg Thieme Verlag: Stuttgart, 2014; pp 311-331.

18

CN additions to C=O and C=N bonds. Merino, P., In Comprehensive Organic Synthesis 2nd ed., Knochel, P.; Molander, G. A., Eds. Elsevier: Oxford, 2014; Vol. 1, pp 697-750.

17

Recent advances in the chemical synthesis of aza-nucleosides. Tejero, T.; Delso, I.; Merino, P., In Chemical Synthesis of Nucleoside Analogues, Merino, P., Ed. John Wiley and sons: Hoboken, 2013; pp 699-725.

16

Chemical synthesis of conformationally constrained PNA monomers. Merino, P.; Matute, R., In Chemical Synthesis of Nucleoside Analogues,  Merino, P., Ed. John WIley and sons: Hoboken, 2013; pp 847-880.

15

Nitrones and cyclic analogues. Merino, P., An update. In Science of Synthesis,  Schaumann, E., Ed. George Thieme: Stuttgart, 2011; Vol. 2010/4, pp 325-403.

14

2-(Trimethylsilyl)thiazole, Dondoni, A.; Merino, P.; Sanchez-Sancho, F.; Zarzuelo, M. M.; Garranzo, M. Handbook of Reagents for Organic Synthesis: Reagents for Silicon-Mediated Organic Synthesis 2011, 712-719.

13

Annulated Benzenes (1H-Cyclopropabenzenes, 1,2-Dihydrocyclobutabenzenes, Indanes, and Indenes). Merino, P., In Compounds with All-Carbon Functions. Monocyclic Arenes, Quasiarenes, and Annulenes, Siegel, J. S.; Tobe, Y., Eds. Georg Thieme Verlag: Stuttgart-New York, 2008; Vol. 45a, pp 253-327.

12

Cyclopentadienyl Anions, Cyclopentadienones, and Heteroatom Analogues. Merino, P.,  In Compounds with All-Carbon Functions. Monocyclic Arenes, Quasiarenes, and Annulenes, Siegel, J. S.; Tobe, Y., Eds. Georg Thieme Verlag: Stuttgart-New York, 2008; Vol. 45a, pp 109-156.

11

Cyclopropenium Salts, Cyclopropenones and Heteroatom Analogues, and Cyclopropenyl Radicals and Anions. Merino, P., In Compounds with All-Carbon Functions. Monocyclic Arenes, Quasiarenes, and Annulenes, Siegel, J. S.; Tobe, Y., Eds. Georg Thieme Verlag: Stuttgart-New York, 2008; Vol. 45a, pp 11-48.

10

Acetals OX/OR. Merino, P., In Science of Synthesis, Warriner, S., Ed. George Thieme: Stuttgart, 2007; Vol. 29, pp 707-800.

9

2-(Trimethylsilyl)thiazole - First Update to document cited in CA149:288259, Dondoni, A.; Merino, P.; Sanchez-Sancho, F.; Zarcuelo, M. M.; Garranzo, M. e-EROS Encyclopedia of Reagents for Organic Synthesis 2007, No pp given.

8

Nitrones an its Cyclic Analogues. Merino, P., In Science of Synthesis, Bellus, D.; Padwa, A., Eds. George Thieme: Stuttgart, 2004; Vol. 27, pp 511-580.

7

Benzothiazole, Dondoni, A.; Merino, P. e-EROS Encyclopedia of Reagents for Organic Synthesis 2001, No pp given.

6

2-Methylbenzothiazole, Dondoni, A.; Merino, P. e-EROS Encyclopedia of Reagents for Organic Synthesis 2001, No pp given.

5

2-(Trimethylsilyl)thiazole, Dondoni, A.; Merino, P. e-EROS Encyclopedia of Reagents for Organic Synthesis 2001, No pp given.

4

Thiazoles, Dondoni, A.; Merino, P. Comprehensive Heterocyclic Chemistry II 1996, 3, 373-474.

3

2-(Trimethylsilyl)thiazole. Dondoni, A.; Merino, P., In e-EROS Encyclopedia of Reagents for Organic Synthesis, 1995; pp 5313-5315.

2

2-Methylbenzothiazole. Dondoni, A.; Merino, P., In e-EROS Encyclopedia of Reagents for Organic Synthesis, 1995; pp 3426-3427.

1

Benzothiazole. Dondoni, A.; Merino, P., In e-EROS Encyclopedia of Reagents for Organic Synthesis, 1995; pp 298-300.

 

Edited Books

Chemical Synthesis of Nucleoside Analogues
Pedro Merino (Wiley, ISBN: 978-1-1180-0751-8) \ March 2013. 921 pages
Read more...

Target in Heterocyclic Systems. Vol. 19. 2015
Orazio A. Attanasi, Pedro Merino, Domenico Spinelli
Read more ...


Others

22

Herrera, R. P.; Merino, P. In Uncatalyzed multicomponent synthesis of α-hydrazido phosphonates, Abstracts of Papers, 239th ACS National Meeting, San Francisco, CA, United States, March 21-25, 2010, 2010; pp ORGN-71.

21

¿Por qué no es probable una vida basada en el silicio?, Merino, P. El Esceptico 2006, 82-85.

20

Stereoselective preparation of optically pure methyl 4(R)-N-(tert-butoxycarbonyl)-4-hydroxypyroglutamate, Merino, P.; Franco, S.; Merchan, F.; Revuelta, J.; Tejero, T. International Electronic Conferences on Synthetic Organic Chemistry, 5th, 6th, Sept. 1-30, 2001 and 2002 [and] 7th, 8th, Nov. 1-30, 2003 and 2004 2004, 1268-1273.

19

Professor Enrique Melendez. A tribute, Merino, P. Arkivoc 2004, 1-4.

18

Kappe, O.; Merino, P.; Marzinzik, A.; Wennemers, H.; Wirth, T.; Vanden Eynde, J.-J.; Lin, S.-K. In Proceedings of ECSOC-5. The fifth international electronic conference on synthetic organic chemistry, 2001.

17

Tejero, T.; Anoro, S.; Merchan, F. L.; Merino, P. In 1,3-Dipolar cycloadditions of N-benzyl-C-furfurylnitrones to vinyl ethers and α,β-unsaturated esters, Proceedings. ECSOC-3, Proc. ECSOC-4, 2000; pp 50-58.

16

Crystal and molecular structures of N-benzyl-C-(2-pyridyl) nitrone and its ZnBr2 complex, Merino, P.; Anoro, S.; Tejero, T.; Laguna, M.; Cerrada, E.; Moreno, A. Proceedings of ECSOC-3, [and] Proceedings of ECSOC-4, Sept. 1-30, 1999 and 2000 2000, 502-509.

15

Polyalkoxy nitrones as chiral building blocks in asymmetric synthesis, Merino, P.; Tejero, T. Proceedings of ECSOC-1: The First International Electronic Conference on Synthetic Organic Chemistry; [and] Proceedings of ECSOC-2: The Second International Electronic Conference on Synthetic Organic Chemistry, Sept. 1-30, 1997, 1998 1999, 118-128.

14

Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. In Nucleophilic additions of 2-furyllithium to carbonyl derivatives of L-serine. Formal synthesis of (2R,3R)-β-hydroxy aspartic acid, Proceedings of ECSOC-1: The First International Electronic Conference on Synthetic Organic Chemistry; [and] Proceedings of ECSOC-2: T, 1999; pp 328-334.

13

(1R,2S)-N-benzyl-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)-(2-benzofuryl)methyl]hydroxylamine, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Molecules [Electronic Publication] 1998, 3, M77.

12

(1S,2S)-N-benzyl-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)-(2-benzofuryl)methyl]hydroxylamine, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Molecules [Electronic Publication] 1998, 3, M78.

11

(1R,2S)-N-benzyl-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)-(2-benzothiazolyl)methyl]hydroxylamine, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Molecules [Electronic Publication] 1998, 3, M79.

10

(1S,2S)-N-benzyl-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)-(2-benzothiazolyl)methyl]hydroxylamine, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Molecules [Electronic Publication] 1998, 3, M80.

9

(1R,2S)-N-benzyl-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)-(2-benzothienyl)methyl]hydroxylamine, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Molecules [Electronic Publication] 1998, 3, M81.

8

(1S,2S)-N-benzyl-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)-(2-benzothienyl)methyl]hydroxylamine, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Molecules [Electronic Publication] 1998, 3, M82.

7

(1S,2S)-N-benzyl-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)-(1-methylimidazol-2-yl)methyl]hydroxylamine, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Molecules [Electronic Publication] 1998, 3, M83.

6

(1R,2S)-N-benzyl-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)-(1-methylimidazol-2-yl)methyl]hydroxylamine, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Molecules [Electronic Publication] 1998, 3, M84.

5

(1R,2S)-N-benzyl-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)-(2-thienyl)methyl]hydroxylamine, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Molecules [Electronic Publication] 1998, 3, M85.

4

(1S,2S)-N-benzyl-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)-(2-thienyl)methyl]hydroxylamine, Merino, P.; Franco, S.; Merchan, F. L.; Tejero, T. Molecules [Electronic Publication] 1998, 3, M86.

3

Stereocontrolled nucleophilic additions of lithiated heterocycles to nitrones. Synthesis and structural characterization of novel chiral (hydroxyamino)methyl heterocycles, Merino, P.; Franco, S.; Martinez, I.; Merchan, F. L.; Tejero, T. ECHET98: Electronic Conference on Heterocyclic Chemistry, June 29-July 24, 1998 1998, 35-40.

2

A short and efficient asymmetric synthesis of 5-substituted Δ3-pyrrolin-2-ones. A new approach to 2-pyrrolidones and pyrrolidines, Merino, P.; Merchan, F.; Tejero, T. Electron. Conf. Heterocycl. Chem., [Proc.] 1997, No pp given.

1

Models for the addition of metalated heterocycles to α-amino nitrones, Lanaspa, A.; Merchan, F. L.; Merino, P.; Tejero, T.; Dondoni, A. Electronic Conference on Trends in Organic Chemistry [CD-ROM] 1996, Paper 9.